It seems that some students and a teacher or two got together and wrote a book about infectious disease modelling.  Of particular interest is chapter 4, entitled: When Zombies Attack!: Mathematical Modelling of and Outbreak of Zombie Infection.
You can purchase the book, and I probably would if I had an extra $90 just laying around. Â Or if you want you can read the relevant chapter here. Â But to boil it down, when looking at models of containment, cure and control, the best way to handle a zombie outbreak…
Aim for the head.